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Article

The Weekly Roundup: April 17-21

ICYMI, this week we had stories about melanoma management with pembrolizumab, advances in rosacea therapy, new phase 2 data of VP-315 for BCC, and more.

Phase 2 Data of Personalized Cancer Vaccine With Adjuvant Pembrolizumab for Resected High-Risk Melanoma

Data from the KEYNOTE-942 trial was presented at the American Association for Cancer Research Annual Meeting 2023.

Soda Linked to Higher Risk of Male Baldness

The association was significant after adjusting for sociodemographic factors, hair status, dietary intake, lifestyle, and psychological status.

The Mainstream Patient: April 17

This week's edition of the Mainstream Patient features stories about the risks of phenol peels, the pros and cons of skin cycling, how to prevent stretch marks during pregnancy, and more.

Botanical Blend Demonstrates Efficacy in New Anti-Aging Study

The combination of punica granatum, citrus sinesis, f. cistanche, and centella asiatica revealed improved skin moisturization, radiance, and elasticity in a new study.

POLL: What is the Most Common Causative Agent of Erythema Multiforme?

Click here to answer this week's poll.

Gloves Can Create Skin Irritation, Negative Skin Barrier Effects

Researchers said occlusive materials used in gloves can lead to irritant contact dermatitis.

Cancer Risk in Korean patients With Psoriatic Arthritis Documented

The findings suggest a need to conduct cancer screening by a detailed history and comprehensive clinical examination in patients with PsA.

Prior Immunotherapy May Impact Melanoma Treatment Response

Researchers said responses may depend on prior immunotherapy.

Doris Day, MD, Discusses Primary Axillary Hyperhidrosis and Brella SweatControl Patch

Brella received FDA clearance last week for improving excessive underarm sweating.

FDA Accepts Roflumilast Foam NDA for the Treatment of Seborrheic Dermatitis

The expected PDUFA date is December 16, 2023.

Managing Melasma With Topical Tranexamic Acid

Findings published in JDD suggest topical tranexamic acid can be used as first-line monotherapy.

Antibiotic Resistance in Patients With Rosacea

The American Acne and Rosacea Society is spotlighting the issue as part of Rosacea Awareness Month.

Pointers With Portela: Affordable and Travel-Friendly Skin Care Products

In this week’s Pointers with Portela, the 208SkinDoc picks out affordable and travel-friendly skin care products at Target that everyone can benefit from.

Treatment Disparities in Patients of Color With Hidradenitis Suppurativa

A key factor associated with delayed diagnosis for non-White patients is the lack of awareness that their symptoms are associated with a treatable medical condition, according to Oma Agbai, MD, and Lisa Nyanda-Manalo, MD.

USPSTF Issues New Statement on Skin Cancer Screening

The task force defined screening as a visual skin exam by a primary care clinician for this recommendation.

Renata Block, PA-C, Discusses Recent Interview With the Eczema Sample Store

Block spoke to the founder of the Eczema Sample Store over Instagram Live to bring more awareness to the company’s mission.

Dupilumab Shifts Skin Microbiome Toward Control Levels

Researchers said the drug is capable of restoring a healthy skin biome.

Dermoscopic Features in Melanoma Associated With 3 Genes

Researchers identified several dermoscopic features associated with genes LINC00518, PRAME, and TERT.

Electric Stimulation Found to Accelerate Chronic Wound Healing

Researchers also investigated how electric stimulation could be used to speed up wound healing in connection with diabetes, which affects wound healing due to impaired circulation and nerve damage.

New Safety and Efficacy Data of Ritlecitinib for Alopecia Areata Published in The Lancet

Ritlecitinib was found to be effective and well-tolerated in patients aged 12 years and older.

In Mouse Study, Topical Emollient Reduced Atopic Dermatitis-Like Lesions

Researchers said emollients markedly reduced lesions and other atopic dermatitis-related factors.

Compound Glycyrrhizin Injections More Efficacious in Acne Than Clindamycin

Researchers said using the injections and mesotherapy in patients with acne more effectively treated their acne.

FDA Issues Second CRL for Alvotech’s Adalimumab Biosimilar

Approval has been pushed back to June 28, 2023.

Patient Preferences in Topical Psoriasis Treatment

A new study revealed that psoriasis patient adherence is influenced by certain characteristics of topical medications.

The Impact of Swimming on Atopic Dermatitis Flares

Researchers pooled evidence supporting the way these 2 factors correlate.

1 in 5 With Spontaneous Urticaria Has Celiac Disease Autoantigen Expression

Researchers said expression of the autoantigen was increased in patients.

European Commission Approves Ruxolitinib Cream for Non-Segmental Vitiligo

Ruxolitinib is the first and only approved treatment for repigmentation in the European Union.

Tralokinumab Found to be Efficacious in Adolescents With Moderate to Severe Atopic Dermatitis

Results of the phase 3 ECZTRA 6 trial found that the efficacy of the drug was maintained by more than 50% of patients at 52 weeks.




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