Pigmentary Disorders

In a Dermatology Times Case-Based Roundtable event, Ted Lain, MD, MBA, FAAD, reviewed 2 cases of patients with vitiligo treated with ruxolitinib.

Lal emphasizes the dual approach of combining medical and cosmetic dermatology to effectively address skin issues like hyperpigmentation.

A review examined how vitiligo treatments aim to restore melanocyte function through grafting, phototherapy, immune regulation, antioxidants, and stem cell research.

Researchers found that MBEHQ treatment increased oxidative stress and proinflammatory cytokines IL-1β and IL-18 in patients with vitiligo.

Catch up on the latest news on vitiligo advancements in 2024.

Precision measurements are necessary to improve the current therapeutic armamentarium in pigmentary disorders.

The study is actively recruiting participants at multiple sites across the US.

The study showed significant improvement in repigmentation with silymarin, with patients of different sexes benefiting equally, though monthly differences were not significant.

The 83-year-old patient was being treated for mycosis fungoides.

42 studies with 1027 cases evaluated drugs like bimatoprost and apremilast for vitiligo.

Researchers say further studies are needed to understand the effects of photoactivation, if any, in combination with PRP.

Melasma, challenging due to varied pigmentation in different skin types, requires personalized, tailored care.

The findings highlight the need for diverse genetic studies to understand their broader impact on autoimmune diseases.

Skin with vitiligo and psoriasis shows increased immune cell type, with a Mendelian analysis finding no causal link between the conditions.

Researchers examined the role of diabetes and glycemic profile in the risk of development of vitiligo in a Mendelian randomization study.

Researchers said individuals with vitiligo should monitor for RA and SLE, as regular check-ups are essential for managing this risk.

Rick Guidotti, fashion photographer turned patient advocate, discusses reframing beauty through his nonprofit Positive Exposure.

Silverberg discusses her SPD 2024 lecture, "Approach to Progressive Vitiligo," the future vitiligo landscape, and more.

The study found that CMT is effective and well-tolerated in treating stable vitiligo, with significant positive correlations between the target area treatment ratio and repigmentation.

The study found a genetic link between vitiligo and autoimmune thyroid diseases, but no similar link with autoimmune hepatitis or Graves' disease.

Individuals in Uyo, Nigeria, with albinism are at great risk of developing photodermatoses due to a lack of photoprotection and awareness of photoprotective behaviors.

Today, June 13, is the 10th annual International Albinism Awareness Day.

Conversely, there were higher levels of selenium and folic acid detected in patients with vitiligo versus otherwise healthy individuals.

Data from the TRuE-V mechanism of action study was presented in a poster at the 2024 RAVE Conference.

These findings may provide guidance for future international definitions of degrees of activity and repigmentation in vitiligo.

Clinicians, especially those who see patients with inflammatory and pigmentary disorders, should incorporate alcohol use disorder screening measures into all patient visits.

Topical Bacitracin, Neosporin, and Vaseline were applied to mice over a 6-week period.

In addition, authors of a research letter noted that patients with vitiligo demonstrated a comparable risk of myocardial infarction and cerebrovascular accident.

A new review highlighted JAK inhibitors' role in vitiligo treatment, emphasizing varying benefits, facial efficacy, and potential for sustained responses.

Study participants in the treatment group experienced an observable and significant decrease in melanin index scoring.