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Melanoma mutations spark tailored therapies with impressive response rates
August 1st 2011There is a great need for new melanoma treatments, and there has been some progress in the last five years that has come about as a result of greater molecular understanding of melanoma, according to the director and chairman of the department of dermatology, Skin Cancer Center, University Hospital Essen, Germany.
Proceed with caution before investing in bonds
August 1st 2011If you’ve been following conventional advice on diversification over the past decade, you have a portion of your portfolio invested in bonds of various types. And that’s good. When the equities market tanked in mid-2008, many investors were spared the worst of it by strong returns from their fixed-income investments.
Immunomodulatory antibodies for melanoma treatment prove promising
July 1st 2011Novel immunomodulatory antibodies such as ipilimumab (Bristol-Myers Squibb) and other experimental treatment options such as melanoma vaccines, chemotherapy agents (Abraxane, Celgene) and targeted drug therapies (BRAF inhibitors) are proving effective in the treatment of patients with late-stage melanoma, offering increased hope in the continuing battle against this deadly skin cancer.
How would accountable care organizations impact dermatology?
July 1st 2011In my last editorial, I expressed mystification about what exactly was being "reformed" by the passage of the 2,700-page "Patient Protection and Affordable Care Act." Finally, a limited number of details about the provisions of this act are finally coming to light. The latest is the Accountable Care Organizations (ACOs), which represents one of the first proposals to provide initiatives to reform healthcare delivery.
Lawmaker says Capitol Hill aims to tackle Medicare reimbursement challenges soon
July 1st 2011The fact that Medicare reform is being debated on Capitol Hill and a near 30 percent Medicare physician pay cut looms in January appears to be moving some influential lawmakers to get serious about reforming the system used to pay Medicare doctors. House Energy and Commerce Committee Chairman Fred Upton (R-Mich.) has said a solution is "on the short list of things getting done this summer," and two hearings were held in May as part of that process.
Ablative fractional laser resurfacing associated with pseudomelanoma
July 1st 2011The occurrence of several cases of pseudomelanoma after ablative fractional CO2 laser resurfacing underscore the importance of careful pre- and postoperative evaluation to avoid misdiagnosing a benign lesion as malignant melanoma, says Deborah Sarnoff, M.D.
Topically applied neurotoxin addresses wrinkles without needles
July 1st 2011A groundbreaking topically applied neurotoxin now in phase 2 trials would provide a painless, injection-free wrinkle-relaxing alternative if it is eventually approved by regulators, investigators say. "The product is being developed by Revance and would offer an additional choice for the clinician and the patient," says Michael A.C. Kane, M.D., of Kane Plastic Surgery, New York, and an investigator with the trial. "Many people are needle-phobic and would probably prefer a topical over an injection."
New botulinum toxin expected to challenge cosmetic market leaders
July 1st 2011The safety and dose equivalency of PurTox (Mentor) should place the botulinum toxin head-to-head with Botox when it reaches the U.S. market, according to a European physician who has experience using the pure toxin there. The newcomer, PurTox, is said to be equivalent to the universal comparator Botox (onabotulinumtoxinA, Allergan) in terms of dosing, and, therefore, represents a potential future nemesis for Botox and other toxins on the market.