Zoe Diana Draelos, MD, is a consulting professor of dermatology, Duke University School of Medicine, Durham, N.C. She is investigator, Dermatology Consulting Services, High Point, N.C., and a Dermatology Times Editorial Advisor and co-medical editor.
Formulations 101: Exploring the science behind cosmetic products
September 1st 2009Dapsone has been an important antibiotic in dermatology, especially historically, in the treatment of leprosy. It has been used for both antimicrobial and anti-inflammatory purposes orally, but no topical preparation was ever available. This is because dapsone is neither water- nor oil-soluble, presenting a formulation challenge.
Damage control: Sunburn cell assay used to demonstrate antioxidant abilities of agents
August 1st 2009Antioxidants function to donate an electron to an unstable, highly energetic oxygen species. Thus, they prevent damage. In order to determine the value of a certain antioxidant ingredient, it is necessary to have an evidenced-based, validated method for comparison.