Roflumilast: Mechanism, and Use for Proactive AD Management
November 15th 2024Panelists discuss common misconceptions about the mechanism of action of PDE4 inhibitors in clinical practice, emphasizing that not all PDE4 inhibitors are created equal and how these differences can significantly impact their efficacy and safety profiles.
PDE4 Inhibitor Roflumilast for AD
November 15th 2024Panelists discuss the current landscape of topical treatments for atopic dermatitis, focusing on the evolution of nonsteroidal options over the past decade, and explain the mechanism of action of PDE4 inhibitors in specifically targeting inflammatory pathways associated with the condition.
Comparing the Efficacy of Roflumilast and Crisaborole
November 15th 2024Panelists discuss how topical PDE4 inhibitors compare to traditional treatments like corticosteroids in terms of efficacy, safety, and long-term disease control, while also examining the unique formulations of roflumilast and crisaborole and their implications for skin penetration and patient experience; they highlight practical considerations for application, the management of adverse effects such as stinging and burning, and the distinct advantages of PDE4 inhibitors in addressing specific gaps in atopic dermatitis management for various patient subgroups.
Evolution of Topical Treatment for AD
November 8th 2024Panelists discuss the current landscape of topical treatments for atopic dermatitis, focusing on the evolution of nonsteroidal options over the past decade, and explain the mechanism of action of PDE4 inhibitors in specifically targeting inflammatory pathways associated with the condition.
Case 2: Expert Opinions on Enhancing Patient Education of Vitiligo Treatment Risks and Benefits
December 1st 2023Benjamin Lockshin, MD, FAAD, summarizes the panel's best practices for improving patient education on the risks and benefits of vitiligo treatment. He underscores the importance of establishing and managing expectations for treatment response.
Key Takeaways for the Management of Plaque Psoriasis
Experts in dermatology share final thoughts on the treatment of plaque psoriasis and the ever-changing treatment landscape.
Role of Diversity in Plaque Psoriasis Clinical Trials
Benjamin Lockshin, MD, FAAD, highlights diversity in clinical trials as an unmet need in approaching the treatment of plaque psoriasis.
Plaque Psoriasis Treatment Guidelines
Expert dermatologists discuss the treatment guidelines for plaque psoriasis, and how the decision about treatment is ultimately in the hands of the clinician.
Psychological Impact of Plaque Psoriasis
Nicholas Brownstone, MD, and James Q. Del Rosso, DO, comment on the psychological impact of plaque psoriasis on a patient’s quality of life.
Patient Case #3: 48-Year-Old Male With Plaque Psoriasis
Experts in dermatology review a patient case of a 48-year-old man with plaque psoriasis who is having trouble with topical therapy.
Patient Case #2: 60-Year-Old Female With Chronic Intertrigo
Dermatology experts discuss a patient case concerning a 60-year-old woman with chronic intertriginous psoriasis who is taking a biologic drug for inflammatory bowel disease.
Patient Case #1: 29-Year-Old Female With Plaque Psoriasis
Dawn L. Sammons, DO, FAOCD, FAAD, and Benjamin Lockshin, MD, FAAD, review a case of a female patient with a family history of plaque psoriasis.
Mechanism of Action of Tapinarof in Plaque Psoriasis
Experts discuss the unique mechanism of action of tapinarof and its use in the treatment of plaque psoriasis.
Efficacy of Tapinarof in Plaque Psoriasis
James Q. Del Rosso, DO, and Dawn L. Sammons, DO, FAOCD, FAAD, review the efficacy of a new topical agent in the treatment of plaque psoriasis, tapinarof, highlighting the remittive data.
Treatment Selection in Plaque Psoriasis
Experts in dermatology discuss newer topical treatments, such as tapinarof, in the management of plaque psoriasis.
Topical vs Systemic Therapy in Plaque Psoriasis
Dawn L. Sammons, DO, FAOCD, FAAD, shares her approach to using topical vs systemic therapy in plaque psoriasis, focusing on patient preference as the driving factor for treatment selection.
The Pathogenesis of Plaque Psoriasis
Benjamin Lockshin, MD, FAAD, comments on how the evolution of the pathophysiology of plaque psoriasis has led to more targeted therapies to treat the disease.
Additional Efficacy Findings from the LIBERTY-AD Four-Year Open-Label Extension Study
January 26th 2023Continuing their discussion about efficacy, Andrew F. Alexis, MD, MPH, and Benjamin N. Lockshin, MD, review long-term results on pruritus. Additionally, they explore data for patients who switched from weekly to every-other-week dupilumab treatment.