The Weekly Roundup: August 21-25

Subcutaneous Nodules Misdiagnosed as Pilomatricoma

When children present with nodules, several diagnoses should be considered, including pilomatricoma, vascular tumors, and fibrous tumors.

Frontline Forum Part 3: A Greater Understanding of the Acne Vulgaris Armamentarium

In part 3 of this Frontline Forum series, James Del Rosso, DO; Hilary Baldwin, MD; Neal Bhatia, MD; Christopher Bunick, MD, PhD; Leon Kircik, MD, discuss the use of clascoterone cream 1%, differences in isotretinoin formulations, targeting sebum production, acne guidelines for patient care, and more.

Recognizing and Managing Pediatric Skin Cancer With Early Detection and Education

Although rare, clinicians are encountering more pediatric patients who are at an increased risk of skin cancer due to immunosuppression.

Neuronal-Like Communication Between Non-Neuron Skin Cells May Initiate Melanoma

According to study authors, this electrical communication between skin cells may have the potential for therapeutic implications.

POLL: What Type of Psoriasis Do You Most Commonly Treat in Your Practice?

This Psoriasis Awareness Month, let us know your experiences. Click here to answer this week's poll.

LEO Pharma to Acquire Timber Pharmaceuticals

Timber Pharmaceuticals has been developing TMB-001 for the treatment of congenital ichthyosis.

Skin Microbiota Changes With Sun Exposure

After a minimum 7-day vacation, participants with the highest ultraviolet radiation exposure experienced a decrease in Proteobacteria.

Neck Cream With Retinol, Tripeptide, and Glaucine Increased Collagen

All participants saw an improvement in skin appearance and texture after treatment.

Cosmeceutical Insights 2023: Know What Your Patients Are Searching For

Google Search data analyzed from September 2021 to September 2022 revealed what patients are searching for and the findings may surprise you.

Guidelines for Surgical Treatment of Early-Stage Vulvar Squamous Cell Carcinomas

Collaboration between dermatologists and gynecologists can improve patient quality of life and outcomes in vSCC treatment.

First Patient Dosed in IMG-007 Atopic Dermatitis Study

The OX40 monoclonal antibody possesses an extended half-life. In a previous study, this half-life exceeded that of the average conventional IgG.

CRH-R1 Markedly Increased in Psoriasis, Actinic Keratosis Mast Cells

Investigators noted that there was not a marked increase, however, in keratinocyte skin carcinomas.

Newly Approved Device Improves Periorbital Wrinkles With Minimal Down Time

The Tixel by Sentient eliminates the need for eye protection for patients and providers.

In Rosacea, Botulinum Toxin Requires Further Analysis of Long-Term Clinical Efficacy and Safety

While botulinum toxin has emerged as a treatment course for rosacea in recent years, researchers are calling for more comprehensive and detailed long-term research to assess its effectiveness.

Frontline Forum Part 4: A Greater Understanding of the Acne Vulgaris Armamentarium

In the final part of this Frontline Forum series, James Del Rosso, DO; Hilary Baldwin, MD; Neal Bhatia, MD; Christopher Bunick, MD, PhD; Leon Kircik, MD, discuss the use of clascoterone cream 1%, differences in isotretinoin formulations, targeting sebum production, acne guidelines for patient care, and more.

Pointers With Portela: Skin Care Trivia

In this week’s Pointers With Portela, the 208SkinDoc asks consumers skin care trivia questions about vitamin C, layers of the skin, keratosis pilaris, and more.

Verrica Supports FDA Warning of Unapproved Products to Treat Molluscum Contagiosum

Verrica’s statement follows the FDA’s warning from June 1, 2023.

The ABCs of CBD: Cannabinoids in Dermatology and Skin Care

Cannabis-based personal care products suddenly seem ubiquitous all over the market, where CBD is a featured ingredient in everything from moisturizers and lotions to makeup.

Nivolumab Approved for Treatment of Stage IIB/IIC Melanoma in Europe

Risk of recurrence or death was reduced by 58% compared to placebo.

Reviewing Mast Cell Silencing and Therapeutic Considerations for Chronic Urticaria

The novel therapeutic approach may be promising for patients with the mast cell-dependent disease, which has limited treatment options despite the substantial burden associated with the condition.

Breakthrough Therapy Designation Granted to SD-101 for Treatment of Epidermolysis Bullosa

The topical cream is the first epidermolysis bullosa treatment to receive Breakthrough Therapy designation from the FDA.

Severity of Atopic Dermatitis Increases Disease Burden

Among children and adolescents with atopic dermatitis, higher severity led to more school absences.

Journal Digest: August 24

This week’s collection of the latest dermatologic studies covers PPT5α for androgenetic alopecia, fractional ablative CO2 laser and concurrent isotretinoin treatment for acne scars, vitamin D insufficiency and 25-hydroxy vitamin D levels related to cutaneous melanoma, and a literature review of baricitinib for alopecia areata.

The Beauty-From-Within Market Continues to Grow

The dietary supplement industry seeks to help consumers age gracefully.

Top 4 Clinical Pearls for the Management of Plaque Psoriasis

Alexandra Golant, MD, and Mona Shahriari, MD, shared pearls regarding the role of nonsteroidal topicals in the treatment of plaque psoriasis.

Imiquimod Capable of Detecting Subclinical Actinic Keratosis

As few as 90% of study participants without visible actinic keratosis lesions displayed inflammatory reactions indicative of the presence of subclinical AK lesions.

Research Grant Will Expand Understanding of Dermatological Issues Among Skin of Color

The Sanofi-Regeneron Diversity, Equity, and Inclusion Mid-Career Award applications will open September 15.

Race, Access to Psoriasis Biologics Not Independently Associated

Researchers noted a lack of significant differences in access to biologics among different populations.

Prevention Program Effective in Reducing Patient Burden of Foot Dermatoses

The OCCUPES study examined the patient burden associated with foot dermatoses and work-related skin diseases and the implications of a prevention program.

Shanna Miranti, MPAS, PA-C, Shares Insights on Newly Approved VP-102 for Molluscum Contagiosum

Providers have been eagerly awaiting the approval of VP-102, as molluscum contagiosum accounts for approximately 1% of all diagnosed skin conditions.

Careers in Medicine Event Inspires Young Women to Explore the Medical Field

Attendees learned about a variety of professions in healthcare and how to prepare for them.

Considering Plaque Psoriasis Comorbidities in Treatment Plans

Lauren Miller, MPAS, and T.J. Chao, MPAS, emphasized that clinicians need to be an advocate for patients and take that extra step to educate.