Mount Sinai Experts Author Landmark ‘Seminar’ on Atopic Dermatitis (Eczema) in The Lancet

[Press release provided by Mount Sinai via its Strategic Alliance Partnership with Dermatology Times.]

A leading Mount Sinai expert, Emma Guttman-Yassky, MD, PhD, has co-authored a highly anticipated comprehensive review on atopic dermatitis (eczema), published this week in The Lancet. The article, which the journal called a “seminar,” highlights the immense global burden of atopic dermatitis, the most common chronic inflammatory skin disease, affecting over 200 million individuals worldwide.

Dr. Guttman-Yassky, Waldman Professor and System Chair of the Kimberly and Eric J. Waldman Department of Dermatology at the Icahn School of Medicine at Mount Sinai, collaborated with international dermatology experts Patrick Brunner, MD, MSc, of Mount Sinai and Yael Renert-Yuval, MD, MSc, of Schneider Children’s Medical Center of Israel on the seminar, which provides a state-of-the-art review of this highly common condition, its pathophysiology, and cutting-edge treatments in both adults and children.

“It is an honor to contribute this seminar to The Lancet, which reflects Mount Sinai's leadership in advancing dermatological science and improving patient care,” said Dr. Guttman-Yassky. “Our work provides a comprehensive understanding of the underlying mechanisms that have led to novel treatments for atopic dermatitis, with broad implications for the medical, allergy, and dermatological communities.”

Dr. Brunner added, “We would like to stress that atopic dermatitis doesn’t just affect the skin—it can take a toll on emotional well-being and quality of life. This publication is a step forward in helping clinicians understand and treat this complex condition with the latest therapeutic advances.”

A review article published in The Lancet is highly prestigious, because the journal is one of the world's leading medical journals with a reputation for publishing high-quality research on clinical, public health, and global health topics. This review is an attestation of the Mount Sinai-assembled team’s leadership in research in atopic dermatitis/eczema and its treatment. Mount Sinai has a dedicated eczema center focused on research, clinical trials, and clinical care for adults and children with eczema.

To learn more about the Kimberly and Eric J. Waldman Department of Dermatology at the Icahn School of Medicine at Mount Sinai, please visit: https://icahn.mssm.edu/about/departments-offices/dermatology

Fast Facts About Atopic Dermatitis:

What is it? A common inflammatory skin disease that affects millions of children and adults worldwide.

Symptoms: Red, itchy, and inflamed skin, often linked to a family history of allergies or asthma.

Impact: Can make everyday life difficult, especially for people with severe symptoms.

Other Risks: People with atopic dermatitis are more likely to have other allergic conditions like asthma, food allergies, or hay fever.

New Treatments: Scientists now understand the disease better, leading to advanced treatments like biological drugs and Janus kinase (JAK) inhibitors. These treatments are helping patients find relief when traditional methods fall short.

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About the Icahn School of Medicine at Mount Sinai

The Icahn School of Medicine at Mount Sinai is internationally renowned for its outstanding research, educational, and clinical care programs. It is the sole academic partner for the eight- member hospitals* of the Mount Sinai Health System, one of the largest academic health systems in the United States, providing care to New York City’s large and diverse patient population.

The Icahn School of Medicine at Mount Sinai offers highly competitive MD, PhD, MD-PhD, and master’s degree programs, with enrollment of more than 1,200 students. It has the largest graduate medical education program in the country, with more than 2,600 clinical residents and fellows training throughout the Health System. Its Graduate School of Biomedical Sciences offers 13 degree-granting programs, conducts innovative basic and translational research, and trains more than 500 postdoctoral research fellows.

Ranked 11th nationwide in National Institutes of Health (NIH) funding, the Icahn School of Medicine at Mount Sinai is among the 99th percentile in research dollars per investigator according to the Association of American Medical Colleges.More than 4,500 scientists, educators, and clinicians work within and across dozens of academic departments and multidisciplinary institutes with an emphasis on translational research and therapeutics. Through Mount Sinai Innovation Partners (MSIP), the Health System facilitates the real-world application and commercialization of medical breakthroughs made at Mount Sinai.

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* Mount Sinai Health System member hospitals: The Mount Sinai Hospital; Mount Sinai Beth Israel; Mount Sinai Brooklyn; Mount Sinai Morningside; Mount Sinai Queens; Mount Sinai South Nassau; Mount Sinai West; and New York Eye and Ear Infirmary of Mount Sinai.