Botox activity guides applications

As researchers learn more about botulinum toxin, clinicians continue to refine techniques for treating the upper face, especially in male patients.

"Many men may require higher doses of Botox, up to 80 units in the glabellar area," says Derek H. Jones, M.D., University of California Los Angeles.

One must also keep in mind that male patients have a different ideal aesthetic than females.

Determining how much to add after initial treatments is "where the art of Botox comes in," he says. "Many times, depending on the thickness of the muscle, I'll go up in the glabella to the 40 unit range. If I'm not seeing much result, maybe next time I'll use 60. Very rarely does a patient require 80 units."